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   Insulin Glargine  What is Lantus and Basaglar? Insulin Glargine, also known by the brand names Lantus and Basaglar, is a long-acting man-made insulin that is used to treat diabetes. Unlike regular human insulin, Lantus and Basaglar is an artificially created version of human insulin that is designed to have a predictable and prolonged effect, with little peak action and a relatively flat glucose-lowering profile. How Does Lantus and Basaglar Work? After injection into the subcutaneous tissue just under the skin, Lantus and Basaglar forms microcrystals from which small amounts of insulin are continuously released over an extended period. This provides basal (background) insulin needed by the body throughout the day and night. Lantus and Basaglar has a duration of action of up to 24 hours, allowing once-daily dosing in most patients. The prolonged duration of action is due to two factors - the changes made to the insulin molecule slow absorption from the injectio...

  Dolomite Formation and Composition Dolomite is a carbonate mineral composed primarily of calcium magnesium carbonate. The chemical formula for dolomite is CaMg(CO3)2. It forms when limestone or other carbonate rocks undergo metamorphism due to intense heat and pressure within the earth's crust. During this process, the mineral calcite undergoes a crystal-structure phase transition and is replaced by the it. This reaction typically occurs in presence of magnesium-rich fluids or partial melting of pre-existing ultramafic and mafic igneous rocks. The resulting its rock preserves the original texture and sedimentary structures of the precursor limestone. In terms of composition, pure Dolomite consists of 30.4% magnesium, 21.9% calcium and 47.6% carbon along with oxygen. However, real-world dolomite samples often contain minor impurities and substitutions of other divalent ions such as iron and manganese. The crystal structure of it involves a closely packed arrangement of calciu...

  Spinal Muscular Atrophy What is Spinal Muscular Atrophy? Spinal muscular atrophy (SMA) is a genetic disease that affects the motor nerve cells in the spinal cord, taking away the ability to walk, eat, or breathe. It is a leading genetic cause of death for infants. SMA damages or destroys motor neurons, the nerve cells in the spinal cord that control muscle movement. When motor neurons die, the muscles they control become weak and thin, leading to issues like difficulty holding up the head, sitting up without support, walking or even swallowing. There are different types of SMA classified by severity and age of onset. Types and Genetics of SMA SMA is caused by a mutation or deletion of the survival motor neuron 1 (SMN1) gene. SMN1 produces a protein needed by nerve cells in the spinal cord. There are four primary types of SMA: Type 1 (Werdnig-Hoffmann disease): This is the most severe type of Spinal Muscular Atrophy . Symptoms begin before 6 months of age, and many babies wi...

  KSA Tire A Pioneer in Green Technology KSA Tire has been at the forefront of developing environmentally-friendly tire solutions since its founding in 1995. As one of the first tire manufacturers to incorporate sustainable rubber alternatives and green production processes, KSA recognized early on the need to move the industry toward more eco-friendly options. With rising global concern over pollution and climate change, KSA's focus on innovation has helped establish them as a leader in this important sector. From the start, KSA prioritized using recycled and renewable materials in their tire formulations. One of their earliest breakthroughs was creating a synthetic rubber from used shopping bags and plastic bottles. This groundbreaking "eco-rubber" reduced dependency on petroleum-derived alternatives while diverting waste from landfills. KSA also pioneered the use of agricultural byproducts like natural latex and rice husks as reinforcement fibers. These plant-based ...

Saudi Arabia Pharmaceutical Drugs Market Regulations and Standards in the Saudi Pharma  The Saudi Food and Drug Authority (SFDA) plays a key role in regulating the country's pharmaceutical industry and ensuring drug safety. All pharmaceutical products manufactured or imported into Saudi Arabia must be approved and licensed by the SFDA. The authority has implemented various international quality standards and guidelines to evaluate drugs. Some of the key regulatory requirements for pharmaceutical companies include: - Compliance with Good Manufacturing Practices (GMP): All drug manufacturers operating in Saudi Arabia must adhere to stringent GMP standards set by the World Health Organization and other international bodies. Regular quality inspections are conducted by SFDA officials to ensure compliance. - Clinical trial approval: New drugs must undergo extensive clinical trials in Saudi Arabia to prove safety and efficacy for the local population. Pharmaceutical companies are require...

  Ready To Eat Food Market  The ready to eat food market comprises food items that require minimum or no preparation time before consumption. Ready to eat foods such as frozen meals, frozen pizza, canned meals, snacks, and breakfast cereals are becoming increasingly popular owing to hectic schedules and changing lifestyles. The global ready to eat food market is estimated to be valued at US$ 182.45 Bn in 2024 and is expected to exhibit a CAGR of 12% over the forecast period from 2024 to 2031. Key Takeaways Key players operating in the ready to eat food market are Biogen Inc., AstraZeneca PLC, Pfizer Inc., Novartis International AG, Merck & Co., Inc., Sanofi S.A., F. Hoffmann-La Roche Ltd., Medtronic plc, Boston Scientific Corporation, Abbott Laboratories, Ceregene Inc., BioTime Inc., Stemedica Cell Technologies, Inc., Neuralstem, Inc., and StemCells Inc. These players are focusing on launching new and innovative products to cater to evolving consumer demands. The r...

  Cold Pressed Juice What is Cold Pressed Juice? Cold pressed juice is made by pressing whole fruits and vegetables using a hydraulic press or auger to extract juice slowly without heat or oxidation. This differs from traditional juicing methods like centrifugal juicing which spins produce at high speeds generating heat that can destroy nutrients and enzymes. In this, oxidation is minimized and heat is never used, helping retain up to 30% more vitamins, minerals, antioxidants and phytonutrients compared to other juicing methods. Nutritional Benefits   Due to its gentle extraction method that prevents nutrient degradation, they provides a dense dose of vitamins, minerals and plant compounds. Some key nutritional benefits include: - High in vitamins C, A, K and B-complex vitamins which support immunity, vision, bone health and metabolism. - Rich in minerals like calcium, iron, potassium, magnesium which are important for bone health, blood health, muscle function and hyd...

  Europe pharmaceutical drugs History and growth of the Europe pharmaceutical drugs The pharmaceutical industry has a long history in Europe dating back to the 19th century. Some of the earliest companies established were Bayer in Germany in 1863, followed by Pfizer in the United States in 1850 and another German company Boehringer Ingelheim in 1885. However, it was not until after World War 2 that the sector really began to flourish and establish Europe pharmaceutical drugs dominance on the global stage. Major drivers of the post-war growth included increased funding for medical research from governments eager to improve nationwide health standards. Companies invested heavily in R&D to develop new drugs for widespread diseases and medical conditions. By the 1960s, four of the top ten largest pharmaceutical companies globally were based in Europe. International expansion also accelerated as European firms looked overseas for new markets and opportunities. Today, Europe Ph...

  Gaucher Disease Treatment What is Gaucher Disease? Gaucher disease is a rare inherited disorder that affects certain cells in the body called macrophages. Macrophages are a type of white blood cell that helps fight infection and keeps tissues healthy. In people with Gaucher disease, a fatty substance called glucosylceramide builds up inside macrophages in certain organs and tissues, including the liver, spleen, bone marrow, and sometimes the lungs or brain. There are three main types of Gaucher disease - type 1, type 2, and type 3 - based on whether the person has neurological symptoms and the severity of symptoms. Types of Gaucher Disease: Type 1 Gaucher Disease: This is the most common type. People with type 1 Gaucher disease don't have neurological symptoms. Symptoms may include enlarged spleen and liver, low blood cell counts, bone problems like joint pain and fractures. Type 2 Gaucher Disease: This is the most severe type and is a neurological form of Gaucher disease...

  Global Oropharyngeal Candidiasis Market The Global Oropharyngeal Candidiasis Market involves treatment of fungal infections caused by candida species, especially Candida albicans in the throat and oral cavity. Oropharyngeal candidiasis, commonly known as oral thrush, causes white or yellow plaques in the mouth and throat. It is usually seen in older adults, infants, diabetics, and immunocompromised patients. Antifungal medications are prescribed to clear the infection and relieve symptoms. The antifungal drugs available for treating oropharyngeal candidiasis include miconazole, fluconazole, amphotericin B, nystatin, ketoconazole, voriconazole and echinocandins. The Global Oropharyngeal Candidiasis Market is estimated to be valued at US$ 456 Mn in 2024 and is expected to exhibit a CAGR of 4.1% over the forecast period 2024 to 2031. Increased cases of candida infections due to surge in HIV prevalence and rise in diabetics and cancer patients undergoing chemotherapy has propelled ...

  Oral Thin Films Oral thin films, also known as oral soluble films or oral dissolvable films, are thin polymeric films manufactured using hydrocolloid polymers that rapidly disintegrate when placed on the tongue or buccal cavity. When compared to traditional oral dosage forms like tablets and capsules, oral soluble films have key advantages like rapid disintegration, easy swallowability without water, accurate dosing, and versatility in drug loading. These properties make oral soluble films a promising drug delivery system for a wide range of therapeutic molecules. Composition and Manufacturing of Oral Thin Films Oral Thin Films are typically composed of hydrophilic polymers that are film forming, flexible, and water soluble. Common polymers used include polyvinyl alcohol, pullulan, hydroxypropyl methylcellulose, sodium alginate, and carboxymethyl cellulose. Hydrophobic agents are sometimes added to modulate the mechanical and dissolution properties. Active pharmaceutical ing...

  Medical Elastomers History and Development of Medical Elastomers The origins of modern medical elastomers dates back to the late 19th century when vulcanized rubber was first discovered and began being utilized for various medical devices and applications. Some of the earliest uses included rubber gloves, catheters, and surgical tubing due to rubber's desirable properties including flexibility, elasticity, and ability to create a seal. However, it wasn't until the 1930s-40s that the development of synthetic polymers like silicone and polyurethane accelerated their use in healthcare. During World War II, silicone's heat resistance made it well-suited for applications involving burns treatment and led to advances in skin grafting techniques. In the 1950s, major developments included the first cardiac pacemakers constructed partially from silicone elastomers and the rise of polyvinyl chloride or PVC in medical tubing and blood bags due to its flexibility, resistance to c...