Tacrolimus Market is anticipated to Witness High Growth Owing to Rising Demand for Immunosupressants

The tacrolimus market comprises drugs that suppresses the immune system by blocking T-cell activation. Tacrolimus is majorly used to prevent rejection in organ transplant such as kidney, liver and heart transplants. It works by inhibiting calcineurin, which prevents the activation of T-cells, thereby suppressing the immune system. The increasing organ transplantation procedures and rising awareness regarding organ donation have augmented the demand for immunosuppressants including tacrolimus. As per the statistics provided by the Global Observatory on Donation and Transplantation, around 140,000 solid organ transplantations are performed each year globally. Moreover, the launch of generic versions of tacrolimus drugs has made the treatment affordable and more accessible. The rising prevalence of autoimmune diseases such as rheumatoid arthritis, multiple sclerosis etc. have also propelled the adoption of tacrolimus.

The Global tacrolimus Market is estimated to be valued at US$ 7822.21 Bn in 2024 and is expected to exhibit a CAGR of 7.1% over the forecast period 2024 to 2031.

Tacrolimus Market 
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Key Takeaways

Key players operating in the tacrolimus market are Domtar Corporation, Medline Industries Inc., Cardinal Health, Attends Healthcare Products Inc., Kimberly-Clark Corporation, Dynarex Corporation, Tanga.com, Sarasota Medical, SCA, First Quality Enterprises Inc., Prevail, Cypress Medical Products LLC, Shield Healthcare LLC, 3M, McKesson Corporation, Ontex. The major players are focusing on new product launches, mergers & acquisitions and geographical expansions to gain market share. For instance, in 2020, Mylan N.V. expanded its generics portfolio in Europe with the launch of generic Tacrolimus capsules for organ transplant rejection prevention.

The rising awareness regarding organ donation and listing for transplantation presents significant growth opportunities for players in the tacrolimus market. As per the statistics provided by the organdonor.gov, over 106,000 patients are currently on the national transplant waiting list in the United States. Moreover, the increasing investment by both public and private players in developing novel formulations of tacrolimus with enhanced bioavailability and reduced side effects will further aid the market growth over the forecast period.

Geographically, North America dominates the Global Tacrolimus Market Demand owing to the increasing healthcare expenditure, high awareness about organ transplantation and rising prevalence of autoimmune diseases. However, Asia Pacific is anticipated to exhibit the highest CAGR over the forecast period owing to improving healthcare infrastructure and rising medical tourism in the region. Players are also expanding their presence in developing markets through collaborations with regional partners.

Market Drivers
- Rising number of organ transplantation procedures performed globally every year is the major factor augmenting the demand for immunosupressants like tacrolimus. As per statistics, around 140,000 solid organ transplantations are performed annually worldwide.

Market Restraints
- Higher cost of tacrolimus drugs compared to generic versions can restrain the market growth. Moreover, side effects associated with long term usage of tacrolimus like nephrotoxicity, diabetes mellitus, hypertension can also hamper the adoption of tacrolimus drugs to a certain extent.

Segment Analysis
The tacrolimus market can be segmented by formulation, therapeutic area, distribution channel, and region. Based on formulation, the extended-release capsule segment dominated the market in 2022 and is expected to continue its dominance during the forecast period. Extended-release capsules provide controlled and sustained release of the drug, maintain effective drug levels for a longer duration with reduced dosage, thereby improving patient compliance compared to conventional formulations.

Global Analysis
Regionally, North America accounted for the largest share of the global tacrolimus market in 2022. This is attributed to the rise in organ transplantation procedures, higher per capita income, advanced healthcare infrastructure, and presence of major market players. However, Asia Pacific is expected to witness the highest CAGR during the forecast period owing to growing cases of autoimmune disorders, improving healthcare infrastructure, rising medical tourism, and increasing demand for generic immunosuppressants from emerging economies like India and China. Japan, South Korea and other countries are witnessing increased utilization of tacrolimus owing to rise in aged population susceptible to neurodegenerative and cardiovascular diseases.

 

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