Understanding the Long-Acting Insulin Glargine for Diabetes Treatment
Insulin Glargine What is Lantus and Basaglar? Insulin Glargine, also known by the brand names Lantus and Basaglar, is a long-acting man-made insulin that is used to treat diabetes. Unlike regular human insulin, Lantus and Basaglar is an artificially created version of human insulin that is designed to have a predictable and prolonged effect, with little peak action and a relatively flat glucose-lowering profile. How Does Lantus and Basaglar Work? After injection into the subcutaneous tissue just under the skin, Lantus and Basaglar forms microcrystals from which small amounts of insulin are continuously released over an extended period. This provides basal (background) insulin needed by the body throughout the day and night. Lantus and Basaglar has a duration of action of up to 24 hours, allowing once-daily dosing in most patients. The prolonged duration of action is due to two factors - the changes made to the insulin molecule slow absorption from the injection site, and th