MedInsight Hub

  Europe pharmaceutical drugs History and growth of the Europe pharmaceutical drugs The pharmaceutical industry has a long history in Europe dating back to the 19th century. Some of the earliest companies established were Bayer in Germany in 1863, followed by Pfizer in the United States in 1850 and another German company Boehringer Ingelheim in 1885. However, it was not until after World War 2 that the sector really began to flourish and establish Europe pharmaceutical drugs dominance on the global stage. Major drivers of the post-war growth included increased funding for medical research from governments eager to improve nationwide health standards. Companies invested heavily in R&D to develop new drugs for widespread diseases and medical conditions. By the 1960s, four of the top ten largest pharmaceutical companies globally were based in Europe. International expansion also accelerated as European firms looked overseas for new markets and opportunities. Today, Europe Ph...

  Gaucher Disease Treatment What is Gaucher Disease? Gaucher disease is a rare inherited disorder that affects certain cells in the body called macrophages. Macrophages are a type of white blood cell that helps fight infection and keeps tissues healthy. In people with Gaucher disease, a fatty substance called glucosylceramide builds up inside macrophages in certain organs and tissues, including the liver, spleen, bone marrow, and sometimes the lungs or brain. There are three main types of Gaucher disease - type 1, type 2, and type 3 - based on whether the person has neurological symptoms and the severity of symptoms. Types of Gaucher Disease: Type 1 Gaucher Disease: This is the most common type. People with type 1 Gaucher disease don't have neurological symptoms. Symptoms may include enlarged spleen and liver, low blood cell counts, bone problems like joint pain and fractures. Type 2 Gaucher Disease: This is the most severe type and is a neurological form of Gaucher disease...

  Global Oropharyngeal Candidiasis Market The Global Oropharyngeal Candidiasis Market involves treatment of fungal infections caused by candida species, especially Candida albicans in the throat and oral cavity. Oropharyngeal candidiasis, commonly known as oral thrush, causes white or yellow plaques in the mouth and throat. It is usually seen in older adults, infants, diabetics, and immunocompromised patients. Antifungal medications are prescribed to clear the infection and relieve symptoms. The antifungal drugs available for treating oropharyngeal candidiasis include miconazole, fluconazole, amphotericin B, nystatin, ketoconazole, voriconazole and echinocandins. The Global Oropharyngeal Candidiasis Market is estimated to be valued at US$ 456 Mn in 2024 and is expected to exhibit a CAGR of 4.1% over the forecast period 2024 to 2031. Increased cases of candida infections due to surge in HIV prevalence and rise in diabetics and cancer patients undergoing chemotherapy has propelled ...

  Oral Thin Films Oral thin films, also known as oral soluble films or oral dissolvable films, are thin polymeric films manufactured using hydrocolloid polymers that rapidly disintegrate when placed on the tongue or buccal cavity. When compared to traditional oral dosage forms like tablets and capsules, oral soluble films have key advantages like rapid disintegration, easy swallowability without water, accurate dosing, and versatility in drug loading. These properties make oral soluble films a promising drug delivery system for a wide range of therapeutic molecules. Composition and Manufacturing of Oral Thin Films Oral Thin Films are typically composed of hydrophilic polymers that are film forming, flexible, and water soluble. Common polymers used include polyvinyl alcohol, pullulan, hydroxypropyl methylcellulose, sodium alginate, and carboxymethyl cellulose. Hydrophobic agents are sometimes added to modulate the mechanical and dissolution properties. Active pharmaceutical ing...

  Medical Elastomers History and Development of Medical Elastomers The origins of modern medical elastomers dates back to the late 19th century when vulcanized rubber was first discovered and began being utilized for various medical devices and applications. Some of the earliest uses included rubber gloves, catheters, and surgical tubing due to rubber's desirable properties including flexibility, elasticity, and ability to create a seal. However, it wasn't until the 1930s-40s that the development of synthetic polymers like silicone and polyurethane accelerated their use in healthcare. During World War II, silicone's heat resistance made it well-suited for applications involving burns treatment and led to advances in skin grafting techniques. In the 1950s, major developments included the first cardiac pacemakers constructed partially from silicone elastomers and the rise of polyvinyl chloride or PVC in medical tubing and blood bags due to its flexibility, resistance to c...

  Global Esterquats Market  Esterquats, which are also known as alkyl quaternary ammonium salts, are cationic surfactants that are produced by the quaternization of triethanolamine with fatty acids or methyl esters. Chemically, they are esters of quaternary ammonium salts with fatty acids or esters. Esterquats have good solubility in water and other polar solvents due to the presence of both hydrophilic quaternary ammonium group and hydrophobic long alkyl chain or fatty acid residues. Applications of Esterquats Industry Esterquats find widespread application in the personal care industry, primarily in hair conditioning products such as conditioners and cream rinses. As cationic surfactants, they impart desirable properties like softness, smoothness and manageability to hair. Esterquats also help reduce static electricity in hair and provide heat protection. Their conditioning performance allows manufacturers to formulate products with reduced amounts of silicones. Fabr...

  Foam Trays Foam trays are lightweight plastic food containers typically made from expanded polystyrene foam or polyethylene. They are durable, moisture-resistant and provide protection and insulation for food items. Foam trays first emerged in the 1950s and have since become ubiquitous in the food packaging industry. Their properties make them well-suited for transporting and displaying a variety of foods. Advantages of Foam Trays Industry Some key advantages that have contributed to the popularity of foam trays globally include: Cost-Effectiveness - Foam Trays are relatively inexpensive to manufacture compared to alternative materials like plastic or coated paperboard. Their low production costs help keep food prices low for consumers. Lightweight Nature - Foam trays weigh much less than rigid plastic or coated paperboard trays of the same size. This reduces shipping weights and transportation costs for food producers and retailers. It also lessens the environmental imp...